Construction and activity analyses of single functional mouse peroxiredoxin 6 (Prdx6)

oleh: Wang Lu-Lu, Lu Shi-Ying, Hu Pan, Fu Bao-Quan, Li Yan-Song, Zhai Fei-Fei, Ju Dan-Di, Zhang Shi-Jun, Su Bing, Zhou Yu, Liu Zeng-Shan, Ren Hong-Lin

Format: Article
Diterbitkan: Sciendo 2019-03-01

Deskripsi

Introduction: Peroxiredoxin 6 (Prdx6) is a bifunctional protein with glutathione peroxidase activity and phospholipase A2 activity. Previous studies have shown a significant positive correlation between the intracellular survival ability of Brucella and Prdx6. Here, the Prdx6 enzyme with a single activity was constructed to facilitate study of the relationship between the single function of Prdx6 and Brucella infection.