Low chorionic villous succinate accumulation associates with recurrent spontaneous abortion risk
oleh: Xiao-Hui Wang, Sha Xu, Xiang-Yu Zhou, Rui Zhao, Yan Lin, Jing Cao, Wei-Dong Zang, Hui Tao, Wei Xu, Ming-Qing Li, Shi-Min Zhao, Li-Ping Jin, Jian-Yuan Zhao
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-06-01 |
Deskripsi
Abnormal placentation is associated with recurrent spontaneous abortion (RSA) risk. Here the authors report that low embryonic villous succinate level associates with risk of RSA in patients, and increasing succinate levels is sufficient to reduce the incidence rate in a mouse model of spontaneous abortion.