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Hemangioendothelioma is a vascular tumor that commonly found in soft tissue, lungs, heart, liver, and bones, but it is very rare in bladder. We report a case of pediatric hemangioendothelioma of the bladder in a 2 years 7 months-old boy that treated with total excision of the bladder and bilateral ureterocutaneoustomy. This case is the second case in pediatric patients, and the youngest case that reported in a child. Our patient is doing well post operatively. But unfortunately interferon a-2b is not available in our hospital. At 3 months follow up, there was progressive progression of the tumor. Recurrent Abdominal mass was confirmed by Abdominal CT-Scan. The patient was died one week later. Interferon a-2b is might be an effective regimen on this tumor but further study is needed to confirm this statement.