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Kang Zhao,1 Xinyi Xu,1,2 Hanfei Zhu,1 Ziqi Ren,3 Tianzi Zhang,4 Ningli Yang,5 Shuqin Zhu,1 Qin Xu1 1School of Nursing, Nanjing Medical University, Nanjing, Jiangsu, People’s Republic of China; 2Faculty of Health, The Queensland University of Technology, Brisbane, Queensland, Australia; 3School of Nursing, Fudan University, Shanghai, People’s Republic of China; 4Department of Nursing, Jiangsu College of Nursing, Huai’an, Jiangsu, People’s Republic of China; 5Department of General Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, People’s Republic of ChinaCorrespondence: Qin Xu; Shuqin Zhu Tel +86 13601587208; +86 13851946413Email qinxu@njmu.edu.cn; zsq@njmu.edu.cnBackground: The weight loss in Chinese patients after sleeve gastrectomy is different, and the differences can be evaluated through the trajectories of the percentage of body fat (BF%). Patients’ baseline psychosocial factors may be associated with these trajectories.Materials and Methods: We selected 267 patients who received sleeve gastrectomy for the first time. The BF% at baseline and 1, 3, 6, 12 months after surgery and baseline psychosocial variables were retrospectively collected. The trajectory model was established according to BF% based on the growth mixture model. The baseline psychosocial variables were compared among different trajectory classes.Results: Four types of trajectory classes were obtained. The differences in preoperative dietary self-efficacy, exercise self-efficacy, depression, social support, working status, alcohol consumption, and gender among the classes were statistically significant. The pairwise comparison of the above variables revealed that the differences of gender, dietary self-efficacy and exercise self-efficacy among classes were highly effective.Conclusion: Female gender, low dietary self-efficacy and low exercise self-efficacy were predictors for poor BF% trajectory in sleeve gastrectomy patients. Health professionals can early identify patients who are most likely to lose weight in a not-ideal manner based on the above predictors.Keywords: bariatric surgery, body fat, psychosocial aspects, sleeve gastrectomy, trajectory