Heterogeneous recruitment abilities to RNA polymerases generate nonlinear scaling of gene expression with cell volume
oleh: Qirun Wang, Jie Lin
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-11-01 |
Deskripsi
Expression levels of most genes are proportional to cell volumes, although some genes exhibit nonlinear scaling of expression levels with cell volume. Here the authors provide a model that reveals nonlinear scaling is a direct consequence of heterogeneous recruitment abilities of promoters to RNA polymerases.