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Introduction: Global Harmonized System (GHS), is a system for labeling chemicals. The aim of present study was to investigate the effect of rapid training intervention on student’s awareness toward Global Harmonized System.   Material and Methods: This research was a descriptive-analytical and cross-sectional study conducted among 317 students of Public Health and Allied Medical Sciences faculties of Qazvin University of Medical Sciences in 2016 year. Sampling was done in a random base among the study population.  A general demographic and a global system labeling questionnaires were used for data collection. Training intervention for familiarization with the chemical safety labels, types of chemicals hazardous was implemented using a rapid training method and PowerPoint tool. Data analysis was performed by T-Tests, ANOVA and T-Paired using the SPSS version 18. Results: Allied medical sciences students with an average of 48.31% before training and occupational health students with an average of 94.44% correct answers after the training have the highest awareness on global harmonized system (GHS). The findings also showed that training has a significant effect on the awareness on the international labeling system. Conclusion: The present study showed that initial awareness of the students is low concerning the global harmonized system. So, the prevention of serious accidents in the laboratory environment, the implementation of a short training course would play a significant role in raising students’ awareness about chemical hazards and will control unsafe behaviors during laboratory works.