Genetic implications in vitiligo and vitiligo-associated diseases

oleh: Ana Maria A. STANESCU, Ioana V. GRAJDEANU, Bogdan SERBAN, Ovidiu G. BRATU, Bogdan SOCEA, Anca PANTEA STOIAN, Camelia C. DIACONU

Format: Article
Diterbitkan: Balkan Medical Union 2019-03-01

Deskripsi

Vitiligo is a chronic, asymptomatic, disease that affects the patient from a cosmetic point of view. It is characterized by the appearance of depigmented areas on the skin or mucous membranes. Depending on the morphology of the lesions, vitiligo can be classified into: segmental, non-segmented or mixed. Vitiligo is associated with a range of autoimmune disorders, most commonly autoimmune thyroid diseases, alopecia areata, halo nevi, psoriasis, diabetes, etc. Etiology is not entirely elucidated, autoimmune theory related to specific genetic mutations being the most studied.