Asymmetric azide-alkyne Huisgen cycloaddition on chiral metal surfaces
oleh: Samuel Stolz, Michael Bauer, Carlo A. Pignedoli, Nils Krane, Max Bommert, Elia Turco, Nicolò Bassi, Amogh Kinikar, Néstor Merino-Dìez, Roland Hany, Harald Brune, Oliver Gröning, Roland Widmer
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-04-01 |
Deskripsi
Mechanistic insight into enantioselective reactions at intrinsically chiral surfaces can be challenging to obtain. Here the catalytic activity of Pd1- and Pd3-terminated PdGa{111} surfaces is shown to differ substantially, with Pd1-terminated surfaces promoting on-surface azide– alkyne cycloadditions enantioand regioselectively.