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Establishment of an induced pluripotent stem cell line SDQLCHi048-A from a healthy boy donor
oleh: Ziwen Feng, Xiaomeng Yang, Jingyun Guan, Wei Song, Yi Liu
Format: | Article |
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Diterbitkan: | Elsevier 2023-06-01 |
Deskripsi
The induced pluripotent stem cells (iPSCs) line was generated using peripheral blood mononuclear cells (PBMCs) from a healthy 1-month-old boy. Expression of pluripotency markers, deletion of free episomal vectors, preservation of normal karyotype, and potential for in vitro trilineage differentiation were demonstrated in the iPSCs line SDQLCHi048-A. This cell line may serve as a basis for disease modeling and help to further explore the molecular pathogenesis.