Establishment of an induced pluripotent stem cell line SDQLCHi048-A from a healthy boy donor

oleh: Ziwen Feng, Xiaomeng Yang, Jingyun Guan, Wei Song, Yi Liu

Format: Article
Diterbitkan: Elsevier 2023-06-01

Deskripsi

The induced pluripotent stem cells (iPSCs) line was generated using peripheral blood mononuclear cells (PBMCs) from a healthy 1-month-old boy. Expression of pluripotency markers, deletion of free episomal vectors, preservation of normal karyotype, and potential for in vitro trilineage differentiation were demonstrated in the iPSCs line SDQLCHi048-A. This cell line may serve as a basis for disease modeling and help to further explore the molecular pathogenesis.