The effect of DNA polymorphisms and natural variation on crossover hotspot activity in Arabidopsis hybrids

oleh: Maja Szymanska-Lejman, Wojciech Dziegielewski, Julia Dluzewska, Nadia Kbiri, Anna Bieluszewska, R. Scott Poethig, Piotr A. Ziolkowski

Format: Article
Diterbitkan: Nature Portfolio 2023-01-01

Deskripsi

The effect of sequence polymorphisms on recombination is not fully understood. Here, the authors develop the seed-typing method to map crossovers (COs) by sequencing and show that COs occur preferentially within polymorphic hotspots and that this effect depends on the mismatch repair gene MSH2 in Arabidopsis.