Transposable elements are regulated by context-specific patterns of chromatin marks in mouse embryonic stem cells
oleh: Jiangping He, Xiuling Fu, Meng Zhang, Fangfang He, Wenjuan Li, Mazid Md. Abdul, Jianguo Zhou, Li Sun, Chen Chang, Yuhao Li, He Liu, Kaixin Wu, Isaac A. Babarinde, Qiang Zhuang, Yuin-Han Loh, Jiekai Chen, Miguel A. Esteban, Andrew P. Hutchins
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2019-01-01 |
Deskripsi
Transposable elements (TEs) fulfill essential but poorly understood roles in genome organization and gene expression control. Here the authors show that the regulation of TEs occurs through overlapping epigenetic mechanisms that control the expression and chromatin signatures at TEs.