Therapeutic potential of silymarin as a natural iron‐chelating agent in β‐thalassemia intermedia
oleh: Nahid Reisi, Nafiseh Esmaeil, Marjan Gharagozloo, Behjat Moayedi
| Format: | Article |
|---|---|
| Diterbitkan: | Wiley 2022-01-01 |
Deskripsi
Abstract Abnormal iron accumulation in vital organs is one of the major complications of β‐thalassemia intermedia (β‐TI). Silymarin, a flavonolignan isolated from Silybum marianum, significantly decreases the serum ferritin levels of β‐TI patients. This finding suggests silymarin as a safe and effective natural iron‐chelating agent for the treatment of iron‐overloaded conditions.