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Research question: How much is HIV sero-positivity among residing in the slums of Delhi? Objective: To find out the HIV sero-positivity rate among women residing in slums of Delhi. Study design: Cross-sectional study. Setting: Ante-natal clinics operated by a non-governmental organization in 13 slum communities in East and South Delhi, India Participants: All pregnant women, regardless of gestational period, who had stayed for six months or more in the preceding one year, in the selected slums. Outcome variable: HIV sero-positivity. Results: None of the 1521 blood specimens was positive for HIV antibody. There may have been selection bias. The sample size was inadequate to detect a sero-prevalence of less than 0.5% with 95% C.I. The findings could not be generalised to other population sub-groups.