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Three new furanocembranoids&#8212;briaviodiol F (<b>1</b>) and briaviotriols A (<b>2</b>) and B (<b>3</b>)&#8212;along with a known analogue, briaviodiol A (<b>4</b>), were obtained from a cultured-type octocoral <i>Briareum violaceum</i>. The structures of cembranoids <b>1</b>&#8211;<b>3</b> were elucidated by using spectroscopic methods. In vitro study demonstrated that compounds <b>2</b> and <b>4</b> exerted inhibition effects on inducible nitric oxide synthase (iNOS) release from RAW 264.7, a macrophage cell line that originated from a mouse monocyte macrophage, stimulated with lipopolysaccharides.