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Recently, the beneficial effects of the plants' secondary compounds for the treatment and improvement of diseases have been strongly interested. This study was conducted in a completely randomized design with three replications in the Paveh and Ormanat region of Kermanshah province. For this purpose, after studying the flora of the region, 10 high-widespread families (Apiaceae, Boraginaceae, Lamiaceae, Rosaceae, Solanaceae, Polygonaceae, Fabaceae, Brassicaceae, Liliaceae, and Asteraceae) were selected. In each case, three plant species with three replications were identified and randomly collected during flowering from April to September. Antioxidant potentials of the samples were evaluated by four methods of DPPH, FRAP, ABTS, and TAC. Results of analysis of variance showed significant differences between measured traits in plant species as well as plant family with 99% confidence. Among the studied plants, Pimpinella kotschyana Boiss. from Apiaceae, Bellevalia dichroa Hausskn. from Liliaceae, Muscari neglectum Guss, from Liliaceae showed the highest antioxidant activities using different methods. Results also showed that among the studied plant families, Liliaceae, Rosaceae, Brassicaceae, and Asteraceae showed considerable antioxidant potential and could be noticed in future research.