Interphase chromosomes of the Aedes aegypti mosquito are liquid crystalline and can sense mechanical cues
oleh: VinÃcius G. Contessoto, Olga Dudchenko, Erez Lieberman Aiden, Peter G. Wolynes, José N. Onuchic, Michele Di Pierro
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2023-01-01 |
Deskripsi
Within the nucleus, the genome of eukaryotes folds into partially organized three-dimensional structures specific to each organism. Here the authors perform physical simulations to study the genome architecture of Aedes aegypti, which reveal an ensemble of 3D chromosomal structures that are folded over and partially condensed, resembling liquid crystalline properties.