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With recent advances in medicine, the number of prepubertal and adult males surviving cancer treatment has increased dramatically. This has increased the need to improve the existing technology and search for new fertility preservation options. Presently, only sperm cryopreservation has been accepted in standard clinical practices. Fertility preservation options in prepubertal males are still experimental and there are many unresolved issues related to these technologies. Cryopreseravtion of testicular tissue and spermatogonia! stem cell transplantation should only be offered within 1KB approved clinical protocols after thorough counselling.