SUMO conjugation to the pattern recognition receptor FLS2 triggers intracellular signalling in plant innate immunity

oleh: Beatriz Orosa, Gary Yates, Vivek Verma, Anjil K. Srivastava, Moumita Srivastava, Alberto Campanaro, Daniel De Vega, Alanna Fernandes, Cunjin Zhang, Jack Lee, Malcolm J. Bennett, Ari Sadanandom

Format: Article
Diterbitkan: Nature Portfolio 2018-12-01

Deskripsi

The plant FLS2 receptor initiates bacterial immunity in response to flagellin. Here the authors show that SUMO conjugates to FLS2 in response to flagellin promoting downstream signalling events while Desi3A, an FLS2 deSUMOylating enzyme, is degraded to enhance immune responses.