Nd(OTf)3-catalyzed intramolecular-intermolecular cascade cyclization reaction: An access to phenanthro[9,10-b]furan derivatives

oleh: Hao Dong, Dawen Xu, Wangsheng Liu, Yaopeng Zhang, Hao Guo

Format: Article
Diterbitkan: Elsevier 2019-12-01

Deskripsi

An intramolecular-intermolecular cascade cyclization reaction via multi metal-carbene intermediates has been developed. This reaction uses catalytic amount of Nd(OTf)3, which actives both alkyne and aldehyde moieties. This protocol provides a novel strategy for the synthesis of phenanthro[9,10-b]furans. Keywords: Phenanthro[9,10-b]furan, Cyclization, Neodymium, Heterocycle, Cascade reaction