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Objective Investigating the perspectives and collecting suggestions from medical students on the course of Medical Statistics, as well as their own career development plan and needs, so to provide reference for educational reform. Methods The investigation was implemented with self-made paper questionnaires which contained three parts: personal information, perspectives of Medical Statistics and self-learning condition with career plan. Results Eighty-two percent students (477) are satisfied with the courses of Medical Statistics. Most students believe it as an important course. However, they all think their application skills are relatively weak. Conclusions The cultivation of statistical thinking should be underlined together with a targeted curriculum system suitable for all needs and the implementation of diversified and effective teaching methods.