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Machine learning has become a standard tool for medical researchers attempting to model disease in various ways, including building models to predict response to medications, classifying disease subtypes, and discovering new therapies. In this preview, we review a paper that utilizes quantum computation in order to tackle a critical issue that exists with medical datasets: they are small, in that they contain few samples. The authors’ work demonstrates the possibility that these quantum-based methods may provide an advantage for small datasets and thus have a real impact for medical researchers in the future.