Ionone Derivatives from the Mycelium of Phellinus linteus and the Inhibitory Effect on Activated Rat Hepatic Stellate Cells

oleh: Shiow-Chyn Huang, Ping-Chung Kuo, Hsin-Yi Hung, Tai-Long Pan, Fu-An Chen, Tian-Shung Wu

Format: Article
Diterbitkan: MDPI AG 2016-05-01

Deskripsi

Three new γ-ionylideneacetic acid derivatives, phellinulins A–C (1–3), were characterized from the mycelium extract of Phellinus linteus. The chemical structures were established based on the spectroscopic analysis. In addition, phellinulin A (1) was subjected to the examination of effects on activated rat hepatic stellate cells and exhibited significant inhibition of hepatic fibrosis.