Environmental enrichment preserves a young DNA methylation landscape in the aged mouse hippocampus

oleh: Sara Zocher, Rupert W. Overall, Mathias Lesche, Andreas Dahl, Gerd Kempermann

Format: Article
Diterbitkan: Nature Portfolio 2021-06-01

Deskripsi

Decline of brain function during aging is associated with epigenetic changes, including DNA methylation. Here the authors provide evidence that environmental enrichment delays age-related DNA methylation alterations in the mouse hippocampus.