Neutralization capacity of antibodies elicited through homologous or heterologous infection or vaccination against SARS-CoV-2 VOCs

oleh: Meriem Bekliz, Kenneth Adea, Pauline Vetter, Christiane S. Eberhardt, Krisztina Hosszu-Fellous, Diem-Lan Vu, Olha Puhach, Manel Essaidi-Laziosi, Sophie Waldvogel-Abramowski, Caroline Stephan, Arnaud G. L’Huillier, Claire-Anne Siegrist, Arnaud M. Didierlaurent, Laurent Kaiser, Benjamin Meyer, Isabella Eckerle

Format: Article
Diterbitkan: Nature Portfolio 2022-07-01

Deskripsi

Emerging SARS-CoV-2 variants raise concerns on protective immunity. Here the authors show that convalescent sera from people infected with Alpha, Beta, Gamma or Delta show a significant drop of Omicron-BA.1 neutralization and that vaccine-breakthrough infections with Omicron-BA.1 or Delta result in robust neutralization for both Delta and Omicron-BA.1.