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Rubber Coring of Injectable Medication Vial Stoppers: An Evaluation of Causal Factors
oleh: Chennell Philip, Bourdeaux Daniel, Citerne Quentin, Arnaud Catherine, Cosserant Sylvie, Boiko-Alaux Véra, Sautou Valerie
Format: | Article |
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Diterbitkan: | De Gruyter 2016-12-01 |
Deskripsi
Coring of a medication vial’s rubber stopper has been reported as a major cause of visible particle presence in injectable preparations. In this study, we investigated and quantified visible particle formation caused by coring associated with four potential causal factors.