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<strong>ABSTRACT</strong><br />          Ethyl 2-(1H-imidazol-1-yl)acetate (A₁)  was synthesized by the reaction of ethylchloroacetate with imidazol, Then refluxed with hydrazine hydrate to obtain 2-(1H-imidazol-1-yl)acidhydrazid (A₂) . (A₂)  was reaction  with various substituted benzyldehyd  to gain 6 novel compounds shiffe bases(A_3-8).and 5-(1H-imidazol-1-yl)methyl)3-N-acetyl-2-(aryl)-1,3,4-(2H)-Oxadiazol (A_9-12) were synthesized by the reaction of shiffe bases(A_3-8)with acetic anhydride . In order to show the antibacterial  activity of prepared compounds are evaluated against four types of common bacteria (<em>psedomonus, Staphylococcus aureus, Eschershia coli, Klebsiella peneuomina</em>). The result of biological study are compared with standered antibiotic (metheprem & Gentamycin) . The structure of the synthesized compounds are confirmed by I.R, ¹H-NMR & ¹³C-NMR spectra and Some chemical physical data.