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Cross-Variant Neutralizing Serum Activity after SARS-CoV-2 Breakthrough Infections
oleh: Pinkus Tober-Lau, Henning Gruell, Kanika Vanshylla, Willi M. Koch, David Hillus, Philipp Schommers, Isabelle Suárez, Norbert Suttorp, Leif Erik Sander, Florian Klein, Florian Kurth
Format: | Article |
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Diterbitkan: | Centers for Disease Control and Prevention 2022-05-01 |
Deskripsi
To determine neutralizing activity against the severe acute respiratory syndrome coronavirus 2 ancestral strain and 4 variants of concern, we tested serum from 30 persons with breakthrough infection after 2-dose vaccination. Cross-variant neutralizing activity was comparable to that after 3-dose vaccination. Shorter intervals between vaccination and breakthrough infection correlated with lower neutralizing titers.