Expanding the genome-targeting scope and the site selectivity of high-precision base editors
oleh: Junjie Tan, Fei Zhang, Daniel Karcher, Ralph Bock
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2020-01-01 |
Deskripsi
Base editors can be limited by precision and the size of the target window. Here the authors test Cas9s that recognise alternative PAMs to obtain a series of high-precision editors.