A New Cytotoxic Pregnanone from Calotropis gigantea
oleh: Mao-Yuan Wang, Zhu-Nian Wang, Wen-Li Mei, Zhuang Han, Hao-Fu Dai
| Format: | Article |
|---|---|
| Diterbitkan: | MDPI AG 2008-12-01 |
Deskripsi
A new pregnanone, named calotropone (1), was isolated from the EtOH extract of the roots of Calotropis gigantea L. together with a known cardiac glycoside. The structures were elucidated by a study of their physical and spectral data. Compounds 1 and 2 displayed inhibitory effects towards chronic myelogenous leukemia K562 and human gastric cancer SGC-7901 cell lines.