A cybergenetic framework for engineering intein-mediated integral feedback control systems

oleh: Stanislav Anastassov, Maurice Filo, Ching-Hsiang Chang, Mustafa Khammash

Format: Article
Diterbitkan: Nature Portfolio 2023-03-01

Deskripsi

Homeostasis and robust perfect adaptation are remarkable features of living cells. Here, to synthetically achieve this, the authors present a theoretical and experimental framework using inteins to implement compact biomolecular integral feedback controllers.