Whole-animal genome-wide RNAi screen identifies networks regulating male germline stem cells in Drosophila
oleh: Ying Liu, Qinglan Ge, Brian Chan, Hanhan Liu, Shree Ram Singh, Jacob Manley, Jae Lee, Ann Marie Weideman, Gerald Hou, Steven X. Hou
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2016-08-01 |
Deskripsi
Both intrinsic and external signals regulate stem cell fate. Here, the authors perform a genome-wide RNAi screen to identify regulators of testis germline stem cells (GSC) in Drosophila, finding more than half of the genes were external regulators and heterochromatin/cytokinesis proteins mediated GSC fate.