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Myelin replacement triggered by single-cell demyelination in mouse cortex
oleh: Nicolas Snaidero, Martina Schifferer, Aleksandra Mezydlo, Bernard Zalc, Martin Kerschensteiner, Thomas Misgeld
Format: | Article |
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Diterbitkan: | Nature Portfolio 2020-09-01 |
Deskripsi
Myelination is a highly regulated phenomenon. Here, the authors show that demyelination induced by the loss of a single oligodendrocyte triggers replenishment of a specific fraction the original myelin and myelination of previously unmyelinated axons in the mouse cortex.