Myelin replacement triggered by single-cell demyelination in mouse cortex

oleh: Nicolas Snaidero, Martina Schifferer, Aleksandra Mezydlo, Bernard Zalc, Martin Kerschensteiner, Thomas Misgeld

Format: Article
Diterbitkan: Nature Portfolio 2020-09-01

Deskripsi

Myelination is a highly regulated phenomenon. Here, the authors show that demyelination induced by the loss of a single oligodendrocyte triggers replenishment of a specific fraction the original myelin and myelination of previously unmyelinated axons in the mouse cortex.