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Anaplastic Thyroid Carcinoma (ATC) remains one of the most virulent of all cancers in humans with a survival rate of only 1%. The widespread use of Fine Needle Aspiration Cytology (FNAC) has significantly changed the approach to thyroid nodules and has made it possible to identify such aggressive thyroid neoplasm from aspirated cellular material. ATC can arise from pre-existing well-differentiated thyroid carcinoma. This case is presented due to the rarity of anaplastic carcinoma occurring in Multi-Nodular Goiter (MNG) in an early age group which was diagnosed by FNAC.