Obese mother offspring have hepatic lipidic modulation that contributes to sex-dependent metabolic adaptation later in life

oleh: Christina Savva, Luisa A. Helguero, Marcela González-Granillo, Daniela Couto, Tânia Melo, Xidan Li, Bo Angelin, Maria Rosário Domingues, Claudia Kutter, Marion Korach-André

Format: Article
Diterbitkan: Nature Portfolio 2021-01-01

Deskripsi

Savva et al. investigate the sex dependent effect of maternal obesity on the metabolism of offspring. They find that metabolic changes are conferred on a sex basis, with males suffering from impaired lipid metabolism relative to females when born to obese mothers, using a lipidomic approach.