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Introduction: Bone grafts (Alograft. Autograft and synthetic bonegraft) are used to rapaire bone defects. According to several technical and medical problems . synthetic bone grafts (B.G) are perefered  to others . Nova Bone is an ABG which in more available in Iran, now .So we conducted this study to evaluate it. Methods: 62 Patients with bone defects who needs bone graft during 1 year , under went Nova Bone graft. F/U data we analysed ,according to graft failure and calcium formation. Results : 6 patients out of 62 had been failed to form calcium after 20 weeks of F/U .(9.7%) There were no other Complications (infection and noninfectious) Discussion & Conclusion: Using SBG (including Nova Bone )has been advocated recently due to several problems in cluding Allografts and Autografts. Favorable results (90.3% calcium formation )in patients with Nova Bone grafts (alone or in combination with auto & Allograft)Propose the regular use of it for patients need bone grafts.