Proteotoxicity caused by perturbed protein complexes underlies hybrid incompatibility in yeast
oleh: Krishna B. S. Swamy, Hsin-Yi Lee, Carmina Ladra, Chien-Fu Jeff Liu, Jung-Chi Chao, Yi-Yun Chen, Jun-Yi Leu
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-07-01 |
Deskripsi
Hybrid incompatibility can be an important element of reproductive isolation and speciation. Using chromosome replacement lines of yeast, the authors show that perturbed proteostasis caused by destabilized hybrid protein complexes may represent a general mechanism of hybrid incompatibility.