Single-cell transcriptome profiling of the vaginal wall in women with severe anterior vaginal prolapse
oleh: Yaqian Li, Qing-Yang Zhang, Bao-Fa Sun, Yidi Ma, Ye Zhang, Min Wang, Congcong Ma, Honghui Shi, Zhijing Sun, Juan Chen, Yun-Gui Yang, Lan Zhu
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-01-01 |
Deskripsi
Anterior vaginal prolapse (AVP), the most common form of pelvic organ prolapse, has deleterious effects on women’s health. Here the authors employ single-cell RNA-seq to construct a transcriptomic atlas of vaginal wall cells from AVP patients, and find that extracellular matrix dysregulation and immune reaction are associated with AVP.