Orbitofrontal control of visual cortex gain promotes visual associative learning

oleh: Dechen Liu, Juan Deng, Zhewei Zhang, Zhi-Yu Zhang, Yan-Gang Sun, Tianming Yang, Haishan Yao

Format: Article
Diterbitkan: Nature Portfolio 2020-06-01

Deskripsi

The orbitofrontal cortex (OFC) encodes expected outcomes and plays a key role in outcome-guided behavior. The authors show here that the top-down projection from the OFC to the visual cortex drives visual associative learning by modulating the response gain of V1 neurons to non-relevant stimuli.