Integrative proteogenomic characterization of early esophageal cancer

oleh: Lingling Li, Dongxian Jiang, Qiao Zhang, Hui Liu, Fujiang Xu, Chunmei Guo, Zhaoyu Qin, Haixing Wang, Jinwen Feng, Yang Liu, Weijie Chen, Xue Zhang, Lin Bai, Sha Tian, Subei Tan, Chen Xu, Qi Song, Yalan Liu, Yunshi Zhong, Tianyin Chen, Pinghong Zhou, Jian-Yuan Zhao, Yingyong Hou, Chen Ding

Format: Article
Diterbitkan: Nature Portfolio 2023-03-01

Deskripsi

The progression of oesophageal squamous cell carcinoma (ESCC) from early to advanced stages requires comprehensive molecular characterisation. Here, the authors perform a proteogenomics analysis of ESCC patient samples across nine histopathological stages and three phases, identifying key alterations and paths for progression.