Electrooxidation enables highly regioselective dearomative annulation of indole and benzofuran derivatives

oleh: Kun Liu, Wenxu Song, Yuqi Deng, Huiyue Yang, Chunlan Song, Takfaoui Abdelilah, Shengchun Wang, Hengjiang Cong, Shan Tang, Aiwen Lei

Format: Article
Diterbitkan: Nature Portfolio 2020-01-01

Deskripsi

Enriching the chemical space of polycyclic heterocycles is of high value in chemical biology. Here, the authors report an electrooxidative protocol for the regioselective dearomative annulation of indoles and benzofurans under undivided cell conditions and obtain five- to eight-membered fused heterocycles.