Detection of a 640-bp deletion in the Aggregatibacter actinomycetemcomitans leukotoxin promoter region in isolates from an adolescent of Ethiopian origin

oleh: Rolf Claesson, Jan Gudmundson, Carola Höglund Åberg, Dorte Haubek, Anders Johansson

Format: Article
Diterbitkan: Taylor & Francis Group 2015-04-01

Deskripsi

The expression of the leukotoxin of Aggregatibacter actinomycetemcomitans is regulated by the leukotoxin promoter. A 530-bp deletion or an 886-bp insertion sequence (IS) element in this region has earlier been described in highly leukotoxic isolates. Here, we report on highly leukotoxic isolate with a 640-bp deletion, which was detected in an adolescent of Ethiopian origin.