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We present $\texttt{Qibolab}$, an open-source software library for quantum hardware control integrated with the $\texttt{Qibo}$ quantum computing middleware framework. $\texttt{Qibolab}$ provides the software layer required to automatically execute circuit-based algorithms on custom self-hosted quantum hardware platforms. We introduce a set of objects designed to provide programmatic access to quantum control through pulses-oriented drivers for instruments, transpilers and optimization algorithms. $\texttt{Qibolab}$ enables experimentalists and developers to delegate all complex aspects of hardware implementation to the library so they can standardize the deployment of quantum computing algorithms in a extensible hardware-agnostic way, using superconducting qubits as the first officially supported quantum technology. We first describe the status of all components of the library, then we show examples of control setup for superconducting qubits platforms. Finally, we present successful application results related to circuit-based algorithms.