Arsenic toxicity manifesting as profuse watery diarrhea during induction therapy for acute promyelocytic leukemia
oleh: Ashley Ott, Vinayak Venkataraman, Yousef R. Badran, Rose Goldman, Smiljana Spasic, Darshali A. Vyas, Philip Amrein, Steven McAfee, Andrew Brunner, Amir T. Fathi, Rupa Narayan
| Format: | Article |
|---|---|
| Diterbitkan: | Wiley 2021-05-01 |
Deskripsi
Abstract Arsenic trioxide (ATO) is generally well tolerated for treatment of APL. We present a patient with severe watery diarrhea and pancreatitis thought to be due to ATO toxicity in the setting of obesity and acute kidney injury. Future studies evaluating ATO levels in patients experiencing toxicities may help guide dose modifications.