Coupled binding mechanism of three sodium ions and aspartate in the glutamate transporter homologue GltTk
oleh: Albert Guskov, Sonja Jensen, Ignacio Faustino, Siewert J. Marrink, Dirk Jan Slotboom
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2016-11-01 |
Deskripsi
In neurons and glia, glutamate transporters catalyse the reuptake of this neurotransmitter by coupling it with cation transport. Here the authors combine X-ray crystallography and molecular dynamics simulations of the archeal glutamate transporter GltTkto get insight into the coupled transport mechanism.