The tumour microenvironment shapes dendritic cell plasticity in a human organotypic melanoma culture
oleh: S. Di Blasio, G. F. van Wigcheren, A. Becker, A. van Duffelen, M. Gorris, K. Verrijp, I. Stefanini, G. J. Bakker, M. Bloemendal, A. Halilovic, A. Vasaturo, G. Bakdash, S. V. Hato, J. H. W. de Wilt, J. Schalkwijk, I. J. M. de Vries, J. C. Textor, E. H. van den Bogaard, M. Tazzari, C. G. Figdor
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2020-06-01 |
Deskripsi
Conventional co-culture systems often lack physiological complexity of the tumor microenvironment. Here, the authors report an organotypic skin melanoma culture and use this model to investigate the tumor induced suppression on dendritic cells.