Cryogenic contrast-enhanced microCT enables nondestructive 3D quantitative histopathology of soft biological tissues
oleh: Arne Maes, Camille Pestiaux, Alice Marino, Tim Balcaen, Lisa Leyssens, Sarah Vangrunderbeeck, Grzegorz Pyka, Wim M. De Borggraeve, Luc Bertrand, Christophe Beauloye, Sandrine Horman, Martine Wevers, Greet Kerckhofs
| Format: | Article |
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| Diterbitkan: | Nature Portfolio 2022-10-01 |
Deskripsi
The authors present cryogenic contrast-enhanced MicroCT (cryo-CECT), which by freezing stained samples at optimal freezing rates improves the visualization of the tissue microstructure. They demonstrate quantitative 3D analysis of individual tissue constituents, such as muscle and collagen fibers.