Competing Genetic Traits and Their Influence on LDL Cholesterol Concentration in Familial Hypercholesterolemia
oleh: Christopher Song, MD, Robert S. Rosenson, MD
| Format: | Article |
|---|---|
| Diterbitkan: | Elsevier 2024-01-01 |
Deskripsi
Familial hypercholesterolemia is a monogenic disorder that leads to premature atherosclerosis as a result of lifelong exposure to elevated low-density lipoprotein cholesterol (LDL-C). Both genetic traits and lifestyle factors can influence LDL-C levels. Adults with LDL-C of 170 mg/dL and higher may benefit from genetic evaluation to accurately assess their risk of atherosclerosis.