Spatio-temporal dynamics enhance cellular diversity, neuronal function and further maturation of human cerebral organoids
oleh: Pelin Saglam-Metiner, Utku Devamoglu, Yagmur Filiz, Soheil Akbari, Goze Beceren, Bakiye Goker, Burcu Yaldiz, Sena Yanasik, Cigir Biray Avci, Esra Erdal, Ozlem Yesil-Celiktas
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2023-02-01 |
Deskripsi
Two engineering approaches, a rotating cell culture system (RCCS) and microfluidic platform (ยต-platform), are presented with the goal of improving harvestability, scalability, reproducibility and survival of human brain organoids in long term culture.