Serotype diversity of astroviruses in Rawalpindi, Pakistan during 2009-2010.
oleh: Muhammad Masroor Alam, Adnan Khurshid, Muhammad Suleman Rana, Shahzad Shaukat, Salmaan Sharif, Mehar Angez, Muhammad Naeem, Syed Sohail Zahoor Zaidi
| Format: | Article |
|---|---|
| Diterbitkan: | Public Library of Science (PLoS) 2013-01-01 |
Deskripsi
Astroviruses are globally known enteropathogens causing gastroenteritis and diarrhea, with eight well defined serotypes. Epidemiological studies have recognized serotype-1 as the most common subtype but no such data is available in Pakistan. During 2009-2010, we found astroviruses in 41 out of 535 (7%) samples collected from hospitalized children. Thirty one strains belonged to serotype-1 and clustered into two distinct lineages. Serotype-3, -4 and -6 were detected with 97-98% genetic homology to Indian and Chinese strains.