Inactivating hepatitis C virus in donor lungs using light therapies during normothermic ex vivo lung perfusion
oleh: Marcos Galasso, Jordan J. Feld, Yui Watanabe, Mauricio Pipkin, Cara Summers, Aadil Ali, Robert Qaqish, Manyin Chen, Rafaela V. P. Ribeiro, Khaled Ramadan, Layla Pires, Vanderlei S. Bagnato, Cristina Kurachi, Vera Cherepanov, Gray Moonen, Anajara Gazzalle, Thomas K. Waddell, Mingyao Liu, Shaf Keshavjee, Brian C. Wilson, Atul Humar, Marcelo Cypel
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2019-01-01 |
Deskripsi
Organs from donors with transmissible viral infections, such as hepatitis C virus (HCV), are not offered for transplantation due to a high risk of transmission. Here, Galasso et al. develop a method for treatment of HCV-infected human donor lungs that is safe and prevents HCV transmission in the pig model.